Can anyone give me any advice/info on what it's like working for yourself from home?

I am considering working as a Travel Agent from home a few days a week. I don't want to work full time elsewhere everyday of the week, it's too boring and I want to break up the rountine a bit. I have never worked for myself or from home before, so I am just wondering if people can tell me their experiences? Does it get in the way of your relaxation time when you are at home because you are constantly thinking about doing work from home or do you give yourself set hours and abide by these?